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Dima Biotech

SKU:PME100173

Human CD171 Protein, His Tag

Human CD171 Protein, His Tag

Regular price $389.00 USD
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Size
Target
Uniprot ID
PRODUCT DATA
TARGET

SYNONYMS

CAML1;CD171;HSAS;HSAS1;MASA;MIC5;N-CAM-L1;N-CAML1;NCAM-L1;S10;SPG1

DESCRIPTION

Recombinant Human CD171 Protein with C-terminal 6×His tag

DELIVERY

In Stock

UNIPROT ID

P32004

EXPRESSION HOST

HEK293

TAG

C-6×His Tag

MOLECULAR CHARACTERIZATION

CD171(Ile20-Glu1120) 6×His tag

MOLECULAR WEIGHT

The protein has a predicted molecular mass of 124.0 kDa after removal of the signal peptide.The apparent molecular mass of CD171-His is approximately 130-250 kDa due to glycosylation.

PURITY

The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

FORMULATION & RECONSTITUTION

Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

BACKGROUND

The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of this gene results in multiple transcript variants, some of which include an alternate exon that is considered to be specific to neurons.

USAGE

Research use only

IMAGES

sp-PME100173 CD171 His PAGE 300

Figure 1. Human CD171 Protein, His Tag on SDS-PAGE under reducing condition.

elisa-PME100173 CD171 His ELISA Fig2

Figure 2. ELISA plate pre-coated by 1 μg/mL (100 μL/well) Human CD171 Protein, His Tag(PME100173) can bind Anti-CD171 Rabbit mAb in a linear range of 0.64-16 ng/mL.

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