| TARGET | |
|---|---|
| SYNONYMS |
LAG-3;CD223 |
| DESCRIPTION |
Recombinant Human LAG3 Protein with C-terminal 6×His tag |
| DELIVERY |
In Stock |
| UNIPROT ID |
P18627 |
| EXPRESSION HOST |
HEK293 |
| TAG |
C-6×His Tag |
| MOLECULAR CHARACTERIZATION |
LAG3(Leu23-Leu245) 6×His tag |
| MOLECULAR WEIGHT |
The protein has a predicted molecular mass of 47.0 kDa after removal of the signal peptide. The apparent molecular mass of LAG3-His is approximately 55-70 kDa due to glycosylation. |
| PURITY |
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| BACKGROUND |
Lymphocyte-activation protein 3 belongs to Ig superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. [provided by RefSeq, Jul 2008] |
| USAGE |
Research use only |
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Dima Biotech
SKU:PME100512
Human LAG3 Protein, His Tag
Human LAG3 Protein, His Tag
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$478.00 USD
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PRODUCT DATA
IMAGES

Figure 1. Human LAG3 Protein, His Tag on SDS-PAGE under reducing condition.

Figure 2. ELISA plate pre-coated by 1 μg/ml (100 μl/well) Human LAG3 , His tagged protein (PME100512) can bind Anti-LAG3 Neutralizing antibody (BME100062) in a linear range of 16-80ng/ml.
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