| TARGET | |
|---|---|
| SYNONYMS |
P2X7 |
| DESCRIPTION |
Recombinant human P2RX7 protein with N-terminal human Fc tag |
| DELIVERY |
In Stock |
| UNIPROT ID |
Q99572 |
| EXPRESSION HOST |
HEK293 |
| TAG |
N-Human Fc Tag |
| MOLECULAR CHARACTERIZATION |
hFc(Glu99-Ala330) P2RX7(Ser47-Val334) |
| MOLECULAR WEIGHT |
The protein has a predicted molecular mass of 59.2 kDa after removal of the signal peptide. The apparent molecular mass of hFc-P2RX7 is approximately 55-70 kDa due to glycosylation. |
| PURITY |
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| BACKGROUND |
The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay (NMD) criteria. [provided by RefSeq, Jul 2010] |
| USAGE |
Research use only |
Dima Biotech
SKU:PME100377
Human P2RX7 Protein, hFc Tag
Human P2RX7 Protein, hFc Tag
Regular price
$478.00 USD
Regular price
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$478.00 USD
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PRODUCT DATA
IMAGES
Figure 1. Human P2RX7 Protein, hFc Tag on SDS-PAGE under reducing condition.
