| TARGET | |
|---|---|
| SYNONYMS |
ADABP;ADCP2;CD26;DPPIV;TP103 |
| DESCRIPTION |
Recombinant Human CD26 with C-terminal 6×His tag |
| DELIVERY |
In Stock |
| UNIPROT ID |
P27487 |
| EXPRESSION HOST |
HEK293 |
| TAG |
C-6×His Tag |
| MOLECULAR CHARACTERIZATION |
CD26(Asn29-Pro766) 6×His tag |
| MOLECULAR WEIGHT |
The protein has a predicted molecular mass of 111.5 kDa after removal of the signal peptide.The apparent molecular mass of CD26-His is approximately 100-130 kDa due to glycosylation. |
| PURITY |
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| BACKGROUND |
The DPP4 gene encodes dipeptidyl peptidase 4, which is identical to adenosine deaminase complexing protein-2, and to the T-cell activation antigen CD26. It is an intrinsic type II transmembrane glycoprotein and a serine exopeptidase that cleaves X-proline dipeptides from the N-terminus of polypeptides. Dipeptidyl peptidase 4 is highly involved in glucose and insulin metabolism, as well as in immune regulation. This protein was shown to be a functional receptor for Middle East respiratory syndrome coronavirus (MERS-CoV), and protein modeling suggests that it may play a similar role with SARS-CoV-2, the virus responsible for COVID-19. [provided by RefSeq, Apr 2020] |
| USAGE |
Research use only |
Dima Biotech
SKU:PME100590
Human CD26 (29-766) Protein, His Tag
Human CD26 (29-766) Protein, His Tag
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$411.00 USD
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PRODUCT DATA
IMAGES
Figure 1. Human CD26 Protein, His Tag on SDS-PAGE under reducing condition.
