| TARGET | |
|---|---|
| SYNONYMS |
bA360D14.1;C6orf144;GRAL;UNQ9356 |
| DESCRIPTION |
Recombinant human GFRAL protein with C-terminal 6×His tag |
| DELIVERY |
In Stock |
| UNIPROT ID |
Q6UXV0 |
| EXPRESSION HOST |
HEK293 |
| TAG |
C-6×His Tag |
| MOLECULAR CHARACTERIZATION |
GFRAL(Ser19-Glu351) 6×His tag |
| MOLECULAR WEIGHT |
The protein has a predicted molecular mass of 38.6 kDa after removal of the signal peptide. The apparent molecular mass of GFRAL-His is approximately 35-55 kDa due to glycosylation. |
| PURITY |
The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining. |
| FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| BACKGROUND |
Brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses (PubMed:28953886, PubMed:28846097, PubMed:28846098, PubMed:28846099). Upon interaction with its ligand, GDF15, interacts with RET and induces cellular signaling through activation of MAPK- and AKT- signaling pathways.[UniProtKB/Swiss-Prot Function] |
| USAGE |
Research use only |
Dima Biotech
SKU:PME100621
Human GFRAL Protein, His Tag
Human GFRAL Protein, His Tag
Regular price
$478.00 USD
Regular price
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$478.00 USD
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PRODUCT DATA
IMAGES
Figure 1. Human GFRAL Protein, His Tag on SDS-PAGE under reducing condition.
