| TARGET | |
|---|---|
| SYNONYMS |
IL-17RA;CD217 |
| DESCRIPTION |
Recombinant mouse IL17RA protein with C-terminal 6×His tag |
| DELIVERY |
In Stock |
| UNIPROT ID |
Q60943 |
| EXPRESSION HOST |
HEK293 |
| TAG |
C-6×His Tag |
| MOLECULAR CHARACTERIZATION |
Mouse IL17RA(Ser32-Trp322) 6×His tag |
| MOLECULAR WEIGHT |
The protein has a predicted molecular mass of 34.1kDa after removal of the signal peptide. The apparent molecular mass of mIL17RA-His is approximately 55-70 kDa due to glycosylation. |
| PURITY |
The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining. |
| FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| BACKGROUND |
Receptor for IL17A (PubMed:17911633, PubMed:20554964, PubMed:8777726). Receptor for IL17F (PubMed:17911633, PubMed:20554964). Binds to IL17A with higher affinity than to IL17F (PubMed:17911633). Binds IL17A and IL17F homodimers as part of a heterodimeric complex with IL17RC (By similarity). Also binds heterodimers formed by IL17A and IL17F as part of a heterodimeric complex with IL17RC (By similarity). Receptor for IL17C as part of a heterodimeric complex with IL17RE (PubMed:21993848, PubMed:21993849, PubMed:21982598). Activation of IL17RA leads to induction of expression of inflammatory chemokines and cytokines such as CXCL1, CXCL8/IL8 and IL6 (By similarity).[UniProtKB/Swiss-Prot Function] |
| USAGE |
Research use only |
Dima Biotech
SKU:PME-M100052
Mouse IL17RA Protein, His Tag
Mouse IL17RA Protein, His Tag
Regular price
$660.00 USD
Regular price
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$660.00 USD
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PRODUCT DATA
IMAGES
Figure 1. Mouse IL17RA Protein, His Tag on SDS-PAGE under reducing condition.
