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Dima Biotech

PME100779

Human RSPO1(21-263) Protein, His Tag

Human RSPO1(21-263) Protein, His Tag

$660.00 USD
$660.00 USD
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Size
Target
Uniprot ID
PRODUCT DATA
TARGET

SYNONYMS

R-spondin-1;hRspo1
DESCRIPTION

Recombinant human RSPO1(21-263) protein with C-terminal 6×His tag
DELIVERY

In Stock
UNIPROT ID

Q2MKA7
EXPRESSION HOST

HEK293
TAG

C-6×His Tag
MOLECULAR CHARACTERIZATION

RSPO1(21-263)(Ser21-Ala263) 6×His tag
MOLECULAR WEIGHT

The protein has a predicted molecular mass of 27.6 kDa after removal of the signal peptide. The apparent molecular mass of RSPO1(21-263)-His is approximately 35-55 kDa due to glycosylation.
PURITY

The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
FORMULATION & RECONSTITUTION

Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
BACKGROUND

This gene encodes a secreted activator protein with two cysteine-rich, furin-like domains and one thrombospondin type 1 domain. The encoded protein is a ligand for leucine-rich repeat-containing G-protein coupled receptors (LGR proteins) and positively regulates the Wnt signaling pathway. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
USAGE

Research use only
IMAGES

sp-PME100779 RSPO121 263 His PAGE 300

Figure 1. Human RSPO1(21-263) Protein, His Tag on SDS-PAGE under reducing condition.

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