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Dima Biotech

PME30012

Human CCL1 Protein

Human CCL1 Protein

$503.00 USD
$503.00 USD
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Size
Target
Uniprot ID
PRODUCT DATA
TARGET

SYNONYMS

C-C Motif Chemokine 1;Small-Inducible Cytokine A1;T Lymphocyte-Secreted Protein I-309;CCL1;SCYA1
DESCRIPTION

Recombinant Human C-C Motif Chemokine 1 is produced by our E.coli expression system and the target gene encoding Lys24-Lys96 is expressed.
DELIVERY

In Stock
UNIPROT ID

P22362
EXPRESSION HOST

E.coli
TAG
MOLECULAR CHARACTERIZATION

Not available
MOLECULAR WEIGHT

8.62 KDa
PURITY

Greater than 95% as determined by reducing SDS-PAGE.
FORMULATION & RECONSTITUTION

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
BACKGROUND

Chemokine (C-C Motif) Ligand 1 (CCL1) is a small glycoprotein secreted by activated T cells, which play a central role during immunoregulatory and inflammaion processes. Human CCL1 has been assumed to be a homologue of the mouse TCA3. While the two proteins share only approximately 42% amino acid sequence identity, both chemokines contain an extra pair of cysteine residues not found in most other chemokines. CCL1 attracts monocytes, NK cells, and immature B cells and dendritic cells by interacting with cell surface chemokine receptor CCR8. CCL1 is identified as a potent inhibitor of HIV-1 envelope-mediated cell-cell fusion and virus infection.
USAGE

Research use only
IMAGES

sp-PME30012 C094 P22362 SDS PAGE 0

Figure 1. Greater than 95% as determined by reducing SDS-PAGE.

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