| TARGET | |
|---|---|
| SYNONYMS |
PDGFBB;PDGF-BB |
| DESCRIPTION |
Recombinant Human Platelet-Derived Growth Factor BB is produced by our E.coli expression system and the target gene encoding Ser82-Thr190 is expressed. |
| DELIVERY |
In Stock |
| UNIPROT ID |
P01127 |
| EXPRESSION HOST |
E.coli |
| TAG | |
| MOLECULAR CHARACTERIZATION |
Not available |
| MOLECULAR WEIGHT |
12.42 KDa |
| PURITY |
Greater than 98% as determined by reducing SDS-PAGE. |
| FORMULATION & RECONSTITUTION |
Lyophilized from a 0.2 μm filtered solution of 20mM NaAc-HAc, pH 4.5. |
| STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| BACKGROUND |
Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma.Binding of PDGFB to its receptor elicits a variety of cellular responses. In addition, PDGFB is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound. |
| USAGE |
Research use only |
Dima Biotech
SKU:PME30015
Human PDGF-BB Protein
Human PDGF-BB Protein
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$503.00 USD
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$503.00 USD
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PRODUCT DATA
IMAGES
Figure 1. Greater than 95% as determined by reducing SDS-PAGE.
