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Dima Biotech

PME30025

Human KGF (C-6His) Protein

Human KGF (C-6His) Protein

$503.00 USD
$503.00 USD
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Size
Target
Uniprot ID
PRODUCT DATA
TARGET

SYNONYMS

Fibroblast growth factor 7;FGF-7;Heparin-binding growth factor 7;HBGF-7;Keratinocyte growth factor;FGF7
DESCRIPTION

Recombinant Human Fibroblast Growth Factor 7/Keratinocyte growth factor is produced by our Mammalian expression system and the target gene encoding Cys32-Thr194 is expressed with a 6His tag at the C-terminus.
DELIVERY

In Stock
UNIPROT ID

P21781
EXPRESSION HOST

HEK293
TAG

C-6×His Tag
MOLECULAR CHARACTERIZATION

Not available
MOLECULAR WEIGHT

20 KDa
PURITY

Greater than 95% as determined by reducing SDS-PAGE.
FORMULATION & RECONSTITUTION

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
BACKGROUND

Fibroblast growth factor 7 (FGF7) is a secreted protein which is mainly located in epithelial cells and belongs to the heparin-binding growth factors family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF7 is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. It is possible major paracrine effector of normal epithelial cell proliferation.
USAGE

Research use only
IMAGES

sp-PME30025 CM88 P21781 SDS PAGE 0

Figure 1. Greater than 95% as determined by reducing SDS-PAGE.

elisa-PME30025 CM88 P21781 ELISA 0

Figure 2. Measured in a cell proliferation assay using HaCaT cells. The ED50 for this effect is 10.94 ng/ml.

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