| TARGET | |
|---|---|
| SYNONYMS |
ACPA;AGP7;C-ANCA;CANCA;MBN;MBT;NP-4;NP4;P29;PR-3;PR3 |
| DESCRIPTION |
Recombinant Human PRTN3 Protein with C-terminal 6×His tag |
| DELIVERY |
In Stock |
| UNIPROT ID |
P24158 |
| EXPRESSION HOST |
HEK293 |
| TAG |
C-6×His Tag |
| MOLECULAR CHARACTERIZATION |
PRTN3(Ala26-Pro256) 6×His tag |
| MOLECULAR WEIGHT |
The protein has a predicted molecular mass of 26.2 kDa after removal of the signal peptide. The apparent molecular mass of PRTN3-His is approximately 25-35 kDa due to glycosylation. |
| PURITY |
The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining. |
| FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| BACKGROUND |
Serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) (PubMed:3198760, PubMed:2033050, PubMed:28240246). By cleaving and activating receptor F2RL1/PAR-2, enhances endothelial cell barrier function and thus vascular integrity during neutrophil transendothelial migration (PubMed:23202369). May play a role in neutrophil transendothelial migration, probably when associated with CD177 (PubMed:22266279).[UniProtKB/Swiss-Prot Function] |
| USAGE |
Research use only |
Dima Biotech
SKU:PME101153
Human PRTN3 Protein, His Tag
Human PRTN3 Protein, His Tag
Regular price
$688.00 USD
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$688.00 USD
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PRODUCT DATA
IMAGES
Figure 1. Human PRTN3 Protein, His Tag on SDS-PAGE under reducing condition.
