| TARGET | |
|---|---|
| SYNONYMS |
FzE3 |
| DESCRIPTION |
Recombinant Human FZD7 Protein with N-terminal human Fc tag |
| DELIVERY |
In Stock |
| UNIPROT ID |
O75084 |
| EXPRESSION HOST |
HEK293 |
| TAG |
N-Human Fc Tag |
| MOLECULAR CHARACTERIZATION |
hFc(Glu99-Ala330) FZD7(Gln33-Arg254) |
| MOLECULAR WEIGHT |
The protein has a predicted molecular mass of 50.5 kDa after removal of the signal peptide. The apparent molecular mass of hFc-FZD7 is approximately 55-70 kDa due to glycosylation. |
| PURITY |
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| BACKGROUND |
Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. [provided by RefSeq, Jul 2008] |
| USAGE |
Research use only |
Dima Biotech
SKU:PME101180
Human FZD7 Protein, hFc Tag
Human FZD7 Protein, hFc Tag
Regular price
$411.00 USD
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$411.00 USD
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PRODUCT DATA
IMAGES
Figure 1. Human FZD7 Protein, hFc Tag on SDS-PAGE under reducing condition.
