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Dima Biotech

PME101223

Human SIGLEC5 Protein, His Tag

Human SIGLEC5 Protein, His Tag

$411.00 USD
$411.00 USD
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Size
Target
Uniprot ID
PRODUCT DATA
TARGET

SYNONYMS

CD33L2;CD170;OB-BP2;OBBP2;SIGLEC-5
DESCRIPTION

Recombinant Human SIGLEC5 Protein with C-terminal 6×His tag
DELIVERY

In Stock
UNIPROT ID

O15389
EXPRESSION HOST

HEK293
TAG

C-6×His Tag
MOLECULAR CHARACTERIZATION

SIGLEC5(Glu17-Thr434) 6×His tag
MOLECULAR WEIGHT

The protein has a predicted molecular mass of 47.2 kDa after removal of the signal peptide. The apparent molecular mass of SIGLEC5-His is approximately 55-100 kDa due to glycosylation.
PURITY

The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
FORMULATION & RECONSTITUTION

Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
BACKGROUND

This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion. [provided by RefSeq, Feb 2012]
USAGE

Research use only
IMAGES

uploads-PME101223 SIGLEC5 His PAGE 300

Figure 1. Human SIGLEC5 Protein, His Tag on SDS-PAGE under reducing condition.

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