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Dima Biotech

SKU:DME100053B

Biotinylated Anti-B7-H3 antibody(DM53), Rabbit mAb

Biotinylated Anti-B7-H3 antibody(DM53), Rabbit mAb

Regular price $657.00 USD
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Size
Recommended-dilutions
clonality
PRODUCT DATA
TARGET

SYNONYMS

B7-H3; CD276; B7 homolog 3; B7H3

HOST SPECIES

Rabbit

DESCRIPTION

Biotinylated Anti-B7-H3 antibody(DM53); Rabbit mAb

DELIVERY

2-3 weeks

UNIPROT ID

Q5ZPR3

IGG TYPE

Rabbit IgG

CLONALITY

Monoclonal

REACTIVITY

Human

APPLICATIONS

ELISA; Flow Cyt

PURIFICATION

Purified from cell culture supernatant by affinity chromatography

FORMULATION & RECONSTITUTION

Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

BACKGROUND

The protein encoded by this gene belongs to the immunoglobulin superfamily; and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors; the protein is preferentially expressed only in tumor tissues. Additionally; it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA; and there is an inverse correlation between the expression of this protein and miR29 levels; suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

USAGE

Research use only

IMAGES

antibody-DME100053B Biotinylated Anti B7 H3 antibodyDM53

Figure 1. 1e5 of Expi 293 cell line were stained with 100 μL of 1:1000 diluted Biotinylated Anti-B7-H3 antibody (DM53), Rabbit mAb (Blue histogram) or isotype control (Red histogram) respectively, washed and then stained with Streptavidin APC. The experimental samples were analyzed by flow cytometry.

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