| TARGET | |
|---|---|
| SYNONYMS |
CC-CKR-8; CCR-8; CDw198; CKRL1; CMKBR8; CMKBRL2; CY6; GPRCY6; TER1 |
| HOST SPECIES |
Rabbit |
| DESCRIPTION |
Anti-CCR8 antibody(DM197); Rabbit mAb |
| DELIVERY |
In Stock |
| UNIPROT ID |
P51685 |
| IGG TYPE |
Rabbit IgG |
| CLONALITY |
Monoclonal |
| REACTIVITY |
Human |
| APPLICATIONS |
ELISA; Flow Cyt |
| RECOMMENDED DILUTIONS |
ELISA 1:5000-10000; Flow Cyt 1:100 |
| PURIFICATION |
Purified from cell culture supernatant by affinity chromatography |
| FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| BACKGROUND |
This gene encodes a member of the beta chemokine receptor family; which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309; thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically; this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region. |
| USAGE |
Research use only |
Dima Biotech
SKU:DME100197
Anti-CCR8 antibody(DM197), Rabbit mAb
Anti-CCR8 antibody(DM197), Rabbit mAb
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$438.00 USD
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PRODUCT DATA
IMAGES
Figure 1. Flow cytometry analysis with Anti-CCR8 (DM197) on Expi293 cells transfected with human CCR8 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
