| TARGET | |
|---|---|
| SYNONYMS |
AITR; GITR; TNFRSF18; CD357 |
| HOST SPECIES |
Rabbit |
| DESCRIPTION |
Biotinylated Anti-GITR antibody(DM78); Rabbit mAb |
| DELIVERY |
2-3 weeks |
| UNIPROT ID |
Q9Y5U5 |
| IGG TYPE |
Rabbit IgG |
| CLONALITY |
Monoclonal |
| REACTIVITY |
Human |
| APPLICATIONS |
ELISA; Flow Cyt |
| RECOMMENDED DILUTIONS |
ELISA 1:5000-10000; Flow Cyt 1:100 |
| PURIFICATION |
Purified from cell culture supernatant by affinity chromatography |
| FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| BACKGROUND |
This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation; and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25( )CD4( ) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. |
| USAGE |
Research use only |
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Dima Biotech
SKU:DME100078B
Biotinylated Anti-GITR antibody(DM78), Rabbit mAb
Biotinylated Anti-GITR antibody(DM78), Rabbit mAb
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$657.00 USD
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