| TARGET | |
|---|---|
| SYNONYMS |
OAZON |
| DESCRIPTION |
Human CLDN2 full length protein-synthetic nanodisc |
| DELIVERY |
In Stock |
| UNIPROT ID |
P57739 |
| EXPRESSION HOST |
HEK293 |
| PROTEIN FAMILIES |
Transmembrane |
| PROTEIN PATHWAYS |
Cell adhesion molecules (CAMs), Leukocyte transendothelial migration, Tight junction |
| FORMULATION & RECONSTITUTION |
Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. |
| MOLECULAR WEIGHT |
The human full length CLDN2 protein has a MW of 24.5 kDa |
| BACKGROUND |
This protein belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. This protein is expressed in the intestine. Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene. |
| STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C(Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| USAGE |
Research use only |
Dima Biotech
SKU:FLP100082
Human CLDN2 full length protein-synthetic nanodisc
Human CLDN2 full length protein-synthetic nanodisc
Regular price
$900.00 USD
Regular price
Sale price
$900.00 USD
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PRODUCT DATA
IMAGES
Figure1. Elisa plates were pre-coated with Flag Tag CLDN2-Nanodisc (0.2μg/per well). Serial diluted anti-Flag monoclonal antibody solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-Flag monoclonal antibody binding with CLDN2-Nanodisc is 6.681ng/ml.
Figure2. Human CLDN2-Nanodisc, Flag Tag on SDS-PAGE
