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Dima Biotech

FLP100111

Human CHRM2 full length protein-synthetic nanodisc

Human CHRM2 full length protein-synthetic nanodisc

$900.00 USD
$900.00 USD
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Size
PRODUCT DATA
TARGET

SYNONYMS

HM2
DESCRIPTION

Human CHRM2 full length protein-synthetic nanodisc
DELIVERY

3-4 weeks
UNIPROT ID

P08172
EXPRESSION HOST

HEK293
PROTEIN FAMILIES

Druggable Genome, GPCR, Transmembrane
PROTEIN PATHWAYS

Calcium signaling pathway, Neuroactive ligand-receptor interaction, Regulation of actin cytoskeleton
MOLECULAR WEIGHT

The human full length CHRM2 protein has a MW of 51.5 kDa
FORMULATION & RECONSTITUTION

Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.
STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
BACKGROUND

The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2008]
USAGE

Research use only
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