TARGET | |
---|---|
SYNONYMS |
GLP-2-R; GLP-2R |
DESCRIPTION |
Human GLP2R full length protein-synthetic nanodisc |
DELIVERY |
In Stock |
UNIPROT ID |
O95838 |
EXPRESSION HOST |
HEK293 |
PROTEIN FAMILIES |
Druggable Genome, GPCR, Transmembrane |
PROTEIN PATHWAYS |
Neuroactive ligand-receptor interaction |
MOLECULAR WEIGHT |
The human full length GLP2R protein has a MW of 63.0 kDa |
FORMULATION & RECONSTITUTION |
Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. |
STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
BACKGROUND |
A G protein-coupled receptor that is closely related to the glucagon receptor and binds to glucagon-like peptide-2 (GLP2). Signalling through GLP2 stimulates intestinal growth and increases villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. |
USAGE |
Research use only |
SKU:FLP100113
Human GLP2R full length protein-synthetic nanodisc
Human GLP2R full length protein-synthetic nanodisc
Regular price
$900.00 USD
Regular price
Sale price
$900.00 USD
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PRODUCT DATA
IMAGES
Figure1. Elisa plates were pre-coated with Flag Tag GLP2R-Nanodisc (0.2μg/per well). Serial diluted anti-Flag monoclonal antibody solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-Flag monoclonal antibody binding with GLP2R-Nanodisc is 2.975ng/ml.
Figure2. Human GLP2R-Nanodisc, Flag Tag on SDS-PAGE