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Dima Biotech

FLP100128

Human TRPV1 full length protein-synthetic nanodisc

Human TRPV1 full length protein-synthetic nanodisc

$900.00 USD
$900.00 USD
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Size
PRODUCT DATA
TARGET

SYNONYMS

VR1
DESCRIPTION

Human TRPV1 full length protein-synthetic nanodisc
DELIVERY

3-4 weeks
UNIPROT ID

Q8NER1
EXPRESSION HOST

HEK293
PROTEIN FAMILIES

Druggable Genome, Ion Channels: Transient receptor potential, Transmembrane
PROTEIN PATHWAYS

Neuroactive ligand-receptor interaction
MOLECULAR WEIGHT

The human full length TRPV1 protein has a MW of 94.8 kDa
FORMULATION & RECONSTITUTION

Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.
STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
BACKGROUND

Capsaicin, the main pungent ingredient in hot chili peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. The protein encoded by this gene is a receptor for capsaicin and is a non-selective cation channel that is structurally related to members of the TRP family of ion channels. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo. Four transcript variants encoding the same protein, but with different 5' UTR sequence, have been described for this gene. [provided by RefSeq, Jul 2008]
USAGE

Research use only
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