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Dima Biotech

SKU:FLP100133

Human HRH3 full length protein-synthetic nanodisc

Human HRH3 full length protein-synthetic nanodisc

Regular price $900.00 USD
Regular price Sale price $900.00 USD
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Size
PRODUCT DATA
TARGET

SYNONYMS

GPCR97; HH3R

DESCRIPTION

Human HRH3 full length protein-synthetic nanodisc

DELIVERY

In Stock

UNIPROT ID

Q9Y5N1

EXPRESSION HOST

HEK293

PROTEIN FAMILIES

Druggable Genome, Transmembrane

PROTEIN PATHWAYS

Neuroactive ligand-receptor interaction

MOLECULAR WEIGHT

The human full length HRH3 protein has a MW of 48.7 kDa

FORMULATION & RECONSTITUTION

Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.

STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

BACKGROUND

Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene encodes one of the histamine receptors (H3) which belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and can regulate neurotransmitter release. This receptor can also increase voltage-dependent calcium current in smooth muscles and innervates the blood vessels and the heart in cardiovascular system.

USAGE

Research use only

IMAGES

elisa-FLP100133 HRH3 Fig.1 Elisa 1
Figure1. Elisa plates were pre-coated with Flag Tag HRH3-Nanodisc (0.2μg/per well). Serial diluted anti-Flag monoclonal antibody solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-Flag monoclonal antibody binding with HRH3-Nanodisc is 2.708ng/ml.
page-FLP100133 HRH3 Fig.2 SDS PAGE 1
Figure2. Human HRH3-Nanodisc, Flag Tag on SDS-PAGE

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