Name: Human TLR9 full length protein-synthetic nanodisc
Brand: Dima Biotech
SKU: FLP100146
Price: 900.0 USD
Availability: InStock

TARGET	TLR9
SYNONYMS	CD289
DESCRIPTION	Human TLR9 full length protein-synthetic nanodisc
DELIVERY	In Stock
UNIPROT ID	Q9NR96
EXPRESSION HOST	HEK293
PROTEIN FAMILIES	Druggable Genome, Transmembrane
PROTEIN PATHWAYS	Toll-like receptor signaling pathway
MOLECULAR WEIGHT	The human full length TLR9 protein has a MW of 115.9 kDa
FORMULATION & RECONSTITUTION	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.
STORAGE & SHIPPING	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
BACKGROUND	The protein is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response.
USAGE	Research use only

Item added to your cart

Human TLR9 full length protein-synthetic nanodisc