CD307 (Y319) polyclonal antibody

The multigene family of Fc receptor homologs (FcRHs,CD307) have variable numbers of extracellular immunoglobulin domains of five different subtypes. FcRH immunoregulatory potential is implicated by the presence of consensus tyrosine-based activation or inhibition motifs in their cytoplasmic tails. The protein products of the human and mouse FcRH5 genes, which are also designated Fc receptor-like protein 5, differ in that human FcRH5 comprises 977 amino acids, whereas mouse FcRH5 contains 582 amino acids.