DHRS9 polyclonal antibody

DHRS9 (dehydrogenase/reductase (SDR family) member 9), also known as RDHL, RDH15, RDHTBE, SDR9C4 or RETSDR8, is a 319 amino acid protein that localizes to the membrane of both the microsome and the endoplasmic reticulum and belongs to the short-chain dehydrogenase/reductase family. Expressed at high levels in trachea and epidermis and present at lower levels in brain, colon, heart, lung, testis, placenta and skeletal muscle, DHRS9 functions as a homotetramer that converts both 3-alpha-tetrahydroprogesterone (allopregnanolone) and 3-alpha-androstanediol to dihydroxyprogesterone and is thought to play a role in retinoic acid biosynthesis. Multiple isoforms of DHRS9 exist due to alternative splicing events.