SCP2 polyclonal antibody

Sterol carrier protein 2 (SCP2), also designated nonspecific lipid-transfer protein, mitochondrial precursor, is involved in the non-specific transfer of intracellular sterol and lipid molecules between membranes. A member of the thiolase family, SCP2 may also be involved in regulating steriodogenesis in fibroblasts, peroxisomes, liver and placenta. In the liver it is a cytoplasmic protein but in steroidogenic tissues it localizes with mitochondria. Isoform SCPx is associated with the peroxisome. SCP2 is associated with Zellweger syndrome (cerebro-hepatic-renal syndrome), characterized by peroxisome deficiency and an impairment in plasmalogen and bile acid synthesis.