LIPG polyclonal antibody

The Lipase gene family belongs to one of the most robust genetic superfamilies found in living organisms, which includes esterases and thioesterases. Members of the AB hydrolase subfamily include hepatic lipase (HL), endothelial lipase (EDL or EL), lipoprotein lipase (LPL), pancreatic lipase (PL), gastric lipase (GL) and LCAT. These family members play a crucial role in the metabolism of lipids. Defects in LPL may cause chylomicronemia syndrome or a form of lipoprotein lipase deficiency characterized by hypertriglyceridemia. Endothelial lipase, which also is known as endothelial cell-derived lipase, has both triglyceride and phospholipase activity. This protein, which is synthesized in endothelial cells, can bind heparin. It is expressed primarily in placenta, liver, thyroid, kidney, lung, testis and ovary tissue.