MLF2 polyclonal antibody

MLF proteins play a role in normal hemopoietic differentiation as well as in erythroid/myeloid lineage switching. MLF2 is a ubiquitously expressed, 248-amino acid protein which shares 40% sequence identity with myeloid leukemia factor 1 (MLF1). MLF2 maps to chromosome 12p13, a region that is often associated with translocations in acute leukemias of lymphoid and myeloid origin. However, no alterations in the structure of the MLF2 locus in patients shown to have 12p translocations have been discovered.