TIMMDC1 polyclonal antibody

TIMMDC1 (translocase of inner mitochondrial membrane domain-containing protein 1), also known as Protein M5-14 or C3orf1 (chromosome 3 open reading frame 1), is a 285 amino acid multi-pass mitochondrion membrane protein that has enhanced expression in heart and skeletal muscle. It has been shown that TIMMDC1 expression is high in lung carcinoma cells, with depletion of TIMMDC1 resulting in inhibition of cell migration and proliferation. It is suggested the TIMMDC1 plays a role as a chaperone protein in construction the membrane arm of mitochondrial respiratory complex I.