RBM25 polyclonal antibody

RMB25 (RNA binding motif protein 25), also known as S164, RNPC7, RED120 or fSAP94, is a 784 amino acid protein that contains one PWI domain and one RRM (RNA recognition motif) domain. Localized to the cytoplasm, as well as to nuclear speckles, RBM25 functions as a splicing factor that is thought to stabilize the pre-mRNA-U1 snRNP complex and may couple splicing with mRNA 3'-end formation. The gene encoding RBM25 maps to human chromosome 14, which houses over 700 genes and comprises nearly 3.5% of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease (AD).