PHF19 polyclonal antibody

PHF19 (PHD finger protein 19), also known as PCL3 (polycomb-like 3), is a 580 amino acid protein that contains two PHD-type zinc fingers. PHF19 exists as three alternatively spliced isoforms and functions as a transcriptional repressor. Localizing to nucleus, PHF19 is ubiquitously expressed, with highest expression in placenta, skeletal muscle, kidney, liver and peripheral blood leukocytes. PHF19 is over-expressed in many types of cancers, including colon, skin, lung, rectal, cervical, uterus and liver cancers, as well as in cell lines derived from different stages of melanoma and in glioma cell lines.