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ABCbiolab

SKU:ABCBW07117

GABARAPL2 polyclonal antibody

GABARAPL2 polyclonal antibody

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GABARAPL2 (γ-aminobutyric acid receptor-associated protein-like 2), also known as ATG8, GEF2 (ganglioside expression factor 2), ATG8C or GATE16 (golgi-associated ATPase enhancer of 16 kDa), is a 117 amino acid protein belonging to the MAP1 LC3 family. Localized to Golgi apparatus, GABARAPL2 is ubiquitously expressed. Very high levels of GABARAPL2 are found in brain, heart, prostate, ovary, spleen and skeletal muscle. GABARAPL2 is subject to post-translational modifications, including phosphorylation, which is thought to occur in response to DNA damage by ATM or ATR. GABARAPL2 is involved in intra-Golgi traffic and modulates intra-Golgi transport through coupling between NSF and SNAREs activation. GABARAPL2 interacts with GABAA Rγ2,
NSF, GS28, β Tubulin and ULK1.

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