Ghrelin polyclonal antibody

Small synthetic molecules called growth-hormone secretagogues (GHSs) act through GSH-R to stimulate the release of GH from the pituitary. Ghrelin is an endogenous levels of ligand for the growth hormone secretagogue receptor (GHS-R). Ghrelin and GHRH are involved in the regulation of GH release from the pituitary. GHRH exerts its action through high-affinity GHRH receptors (GHRH-R) present in the anterior pituitary. The acylated peptide of ghrelin specifically releases GH both in vivo and in vitro and is found in stomach tissue. GH plays a crucial role in stimulating and controlling the growth, metabolism and differentiation of many mammalian cell types by modulating the synthesis of multiple mRNA species. The gene encoding ghrelin maps to human chromosome 3p26-p25.