Histone Deacetylase 6 (phospho-S22) polyclonal antibody

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4) (PubMed:10220385).Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events (PubMed:10220385).Histone deacetylases act via the formation of large multiprotein complexes (PubMed:10220385).