ADM polyclonal antibody

Adrenomedullin (ADM), a vasodilator produced by most contractile cells, is
characterized by persistent hypotensive activity. ADM is involved in the
regulation of fluid and electrolyte homeostasis and the maintenance of
cardiovascular functioning, and in hypertensive patients, the level of ADM
in plasma is upregulated. Natriuresis is a common systemic manifestation of
aneurysmal subarachnoid hemorrhage. ADM has strong natriuretic actions and
ADM-induced natriuresis is caused by an increase in glomerular filtration rate
and a decrease in distal tubular sodium reabsorption. ADM is present both in
the periphery and brain, and this peptide can exert central effects such as
decreasing food ingestion.