GPR150 (Q391) polyclonal antibody

G protein-coupled receptors (GPCRs), also designated seven transmembrane (7TM) receptors and heptahelical receptors, are a protein family which interact with G proteins (heterotrimeric GTPases) to synthesize intracellular second messengers such as diacylglycerol, cyclic AMP, inositol phosphates, and calcium ions. Their diverse biological functions range from vision and olfaction to neuronal and endocrine signaling and are involved in many pathological conditions. G protein receptor 150 (GPR150), also designated PGR11 and seven transmembrane helix receptor, is a member of the rhodopsin family of GCPRs and is involved in signal transduction. GPR150 is expressed in various human tissues, including normal small intestine, skeletal muscle, kidney and tonsil, as well as cancerous blood, bladder, placenta and parathyroid.