GPR152 polyclonal antibody

G protein-coupled receptors (GPRs or GPCRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, are members of the largest protein family and play a role in many different stimulus-response pathways. G protein-coupled receptors mediate extracellular signals into intracellular signals (G protein activation). They respond to a wide variety of signaling molecules, including hormones, neurotransmitters and other proteins and peptides. GPR proteins are usually integral seven pass membrane proteins with some conserved amino acid regions. GPR-152 (G proteincoupled receptor 152) is a 511 amino acid multi-pass membrane protein that belongs to the G-protein coupled receptor 1 family. Encoded by a gene on human chromosome 11q13.2 and mouse chromosome 19 A, GPR-152 may function as an orphan receptor.