PEX11G polyclonal antibody

Peroxisomes are single-membrane bound organelles present in virtually all eukaryotic cells. They are involved in numerous catabolic and anabolic pathways, including beta-oxidation of very long chain fatty acids, metabolism of hydrogen peroxide, plasmalogen biosynthesis and bile acid synthesis. The Peroxin family, which includes more than 20 members, is required for peroxisome biogenesis. The Peroxin 11 peroxisomal membrane proteins are the only factors known to promote peroxisome division in multiple species. Peroxin 11 proteins have a direct role in peroxisomal fatty acid oxidation and only affect peroxisome abundance indirectly. Peroxin 11γ (peroxisomal biogenesis factor 11 gamma), also known as PEX11G or Peroxin-11C, is a 241 amino acid multi-pass membrane protein that belongs to the peroxin 11 family. Peroxin 11γ exist as two isoforms due to alternative splicing events.