HNRNPLL polyclonal antibody

Heterogeneous nuclear ribonucleoprotein L-like (hnRNP LL) is a nuclear RNA-binding protein that shares 69% amino acid homology with hnRNP L, a component of the hnRNP complex that regulates mRNA formation, packaging, and processing. hnRNP LL is induced in activated T cells and functions as a critical regulator of alternative splicing of CD45, a tyrosine phosphatase crucial for T cell development and activation. hnRNP LL also regulates the splicing of CD44 and Stat5a. The four isoforms of hnRNP LL are generated by alternative splicing and are widely expressed in human tissues.