ADAM32 (N530) polyclonal antibody

ADAM (disintegrin and metalloproteinase domain) proteins, also known as MDC (metalloproteinase, disintegrin and cysteine-rich domain) proteins or cellular disintegrins, are a family of proteins that are expressed in numerous tissues. ADAMs are membrane-anchored, glycosylated, Zn2+ dependent proteases that catalyze proteolysis, adhesion, fusion and intracellular signaling. The ADAM family consists of more than 30 different members with many diverse functions. ADAM32 is expressed predominantly in the testis on the sperm surface. The ADAM32 precursor originates in the testis and is processed during epididymal maturation. ADAM32 may play a role in sperm-egg adhesion or sperm development.