CXCL11 polyclonal antibody

IFN-inducible T cell a chemoattractant (I-TAC), also designated βR1, H174, SCYB9B, Scyb11 (mouse), IP-9 or CXCL11, is a member of the CXC chemo-kine family and is expressed in IFN-gamma-treated astrocytes, monocytes, keratin-ocytes, bronchial epithelial cells and neutrophils. The gene encoding I-TAC maps to human chromosome 4q21.2. I-TAC and two related proteins, IFN-induced protein of 10 kDa (IP-10) and monokine induced by IFN-gamma (MIG), belong to the non-glutamate-leucine-arginine motif CXC chemokine family and act solely through the CXCR-3 receptor for potent attraction of T lymphocytes. I-TAC is assumed to be involved in inflammatory diseases characterized by the presence of activated T cells.