APC Anti-Mouse CD117 Antibody[2B8]

APC Anti-Mouse CD117 Antibody[2B8]

The APC Anti-Mouse CD117 Antibody[2B8] is a highly specific monoclonal antibody that targets the CD117 antigen, also known as c-Kit. This antibody is conjugated with APC, a fluorescent dye that allows for easy detection and analysis of CD117-expressing cells by flow cytometry. The CD117 antigen is a transmembrane receptor tyrosine kinase that plays a crucial role in the development and maintenance of hematopoietic stem cells, melanocytes, and germ cells. It is also expressed in a variety of cancers, including gastrointestinal stromal tumors (GISTs), acute myeloid leukemia (AML), and some types of lung cancer.

The APC Anti-Mouse CD117 Antibody[2B8] has been extensively validated for use in various applications, including flow cytometry, immunohistochemistry, and western blotting. It has been shown to specifically recognize mouse CD117 with high sensitivity and specificity, making it an ideal tool for studying the expression and function of CD117 in various biological systems. This antibody has also been used in preclinical studies to evaluate the efficacy of CD117-targeted therapies in cancer models.

In summary, the APC Anti-Mouse CD117 Antibody[2B8] is a highly specific and sensitive monoclonal antibody that targets the CD117 antigen. It is conjugated with APC, allowing for easy detection and analysis of CD117-expressing cells by flow cytometry. This antibody has been extensively validated for use in various applications and has been shown to be a valuable tool for studying the expression and function of CD117 in various biological systems, as well as for evaluating the efficacy of CD117-targeted therapies in cancer models.