KPNA3 Polyclonal Antibody

KPNA3 Polyclonal Antibody

The KPNA3 polyclonal antibody is a highly specific and sensitive tool for the detection and quantification of KPNA3 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human KPNA3 protein. The resulting polyclonal antibody is purified using a combination of protein A and protein G affinity chromatography to ensure high purity and specificity.

The KPNA3 protein is a member of the karyopherin alpha family, which plays a crucial role in the nuclear import of proteins. KPNA3 specifically recognizes and binds to nuclear localization signals (NLS) on cargo proteins, facilitating their transport into the nucleus. Dysregulation of KPNA3 expression has been implicated in various diseases, including cancer and viral infections.

The KPNA3 polyclonal antibody has been extensively validated for use in various applications, including western blotting, immunohistochemistry, and immunofluorescence. It has been shown to specifically detect KPNA3 protein in various human tissues and cell lines, with minimal cross-reactivity with other karyopherin alpha family members.

In summary, the KPNA3 polyclonal antibody is a reliable and sensitive tool for the detection and quantification of KPNA3 protein in various biological samples. Its high specificity and sensitivity make it an ideal choice for researchers studying the role of KPNA3 in various physiological and pathological processes.