KRT13 Polyclonal Antibody

KRT13 Polyclonal Antibody

The KRT13 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of Keratin 13 (KRT13) protein expression in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to a region within the N-terminal domain of the human KRT13 protein.

Keratin 13 is a member of the intermediate filament family of proteins and is predominantly expressed in epithelial tissues, particularly in stratified squamous epithelia. It plays a crucial role in maintaining the structural integrity and mechanical strength of these tissues. Aberrant expression or mutations in KRT13 have been associated with various pathological conditions, including oral squamous cell carcinoma, esophageal squamous cell carcinoma, and skin disorders.

The KRT13 Polyclonal Antibody has been extensively validated for its specificity and sensitivity in various experimental techniques, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits minimal cross-reactivity with other keratin isoforms, ensuring accurate and reliable results. This antibody recognizes both the native and denatured forms of KRT13, making it suitable for a wide range of applications.

With its high affinity and excellent performance, the KRT13 Polyclonal Antibody offers researchers a valuable tool for investigating the expression and localization of KRT13 in normal and diseased tissues. Its application in clinical research may contribute to a better understanding of the molecular mechanisms underlying various epithelial disorders and potentially aid in the development of diagnostic and therapeutic strategies.

In summary, the KRT13 Polyclonal Antibody is a reliable and versatile reagent that enables precise detection and analysis of KRT13 protein expression. Its exceptional specificity, sensitivity, and compatibility with multiple experimental techniques make it an indispensable tool for researchers in the fields of molecular biology, pathology, and clinical research.