ITPKB Polyclonal Antibody

ITPKB Polyclonal Antibody

The ITPKB Polyclonal Antibody is a highly specific and sensitive antibody that has been developed for the detection of inositol-trisphosphate 3-kinase B (ITPKB) protein. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human ITPKB protein. The resulting polyclonal antibody has been purified using protein A affinity chromatography and is suitable for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The ITPKB protein is a member of the inositol phosphate kinase family, which plays a crucial role in the regulation of intracellular signaling pathways. ITPKB specifically catalyzes the phosphorylation of inositol 1,4,5-trisphosphate (IP3) to inositol 1,3,4,5-tetrakisphosphate (IP4), which is involved in the regulation of calcium signaling and cellular metabolism. Dysregulation of ITPKB expression has been implicated in various diseases, including cancer, autoimmune disorders, and neurological disorders.

The ITPKB Polyclonal Antibody has been extensively validated for its specificity and sensitivity in detecting ITPKB protein in various human tissues and cell lines. This antibody has been shown to specifically recognize the endogenous ITPKB protein and does not cross-react with other members of the inositol phosphate kinase family. The high specificity and sensitivity of this antibody make it an ideal tool for studying the expression and function of ITPKB protein in various biological systems.

In summary, the ITPKB Polyclonal Antibody is a highly specific and sensitive antibody that has been developed for the detection of ITPKB protein. This antibody is suitable for use in various applications and has been extensively validated for its specificity and sensitivity. The use of this antibody will facilitate the study of the role of ITPKB in various biological processes and diseases.