KCNJ15 Polyclonal Antibody

KCNJ15 Polyclonal Antibody

The KCNJ15 polyclonal antibody is a highly specific and sensitive tool for the detection and quantification of KCNJ15 protein expression in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human KCNJ15 protein. The resulting polyclonal antibody is purified using a combination of protein A and protein G affinity chromatography to ensure high purity and specificity.

The KCNJ15 protein, also known as Kir4.2, is a member of the inwardly rectifying potassium channel family and is primarily expressed in the brain, spinal cord, and retina. It plays a crucial role in regulating potassium ion homeostasis and neuronal excitability. Dysregulation of KCNJ15 expression has been implicated in various neurological disorders, including epilepsy, migraine, and schizophrenia.

The KCNJ15 polyclonal antibody has been extensively validated for use in various applications, including western blotting, immunohistochemistry, and immunofluorescence. It has been shown to specifically recognize the KCNJ15 protein in human, mouse, and rat tissues, with minimal cross-reactivity with other potassium channel family members.

This antibody is supplied as a liquid formulation in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative. It is available in various sizes to suit different experimental needs. The KCNJ15 polyclonal antibody is a valuable tool for researchers studying the role of KCNJ15 in neurological disorders and for the development of novel therapeutic strategies targeting this protein.