ITGAX Polyclonal Antibody

ITGAX Polyclonal Antibody

The ITGAX polyclonal antibody is a highly specific and sensitive tool for the detection and quantification of ITGAX protein expression in various biological samples. This antibody is produced by immunizing animals with a synthetic peptide corresponding to a specific region of the ITGAX protein sequence. The resulting polyclonal antibody is purified using a combination of affinity chromatography and protein A/G purification methods to ensure high purity and specificity.

The ITGAX protein, also known as CD11c, is a transmembrane glycoprotein that is primarily expressed on the surface of dendritic cells, monocytes, and macrophages. It plays a crucial role in the immune response by mediating cell adhesion and migration, as well as antigen presentation to T cells. Dysregulation of ITGAX expression has been implicated in various diseases, including autoimmune disorders, cancer, and infectious diseases.

The ITGAX polyclonal antibody is suitable for use in a variety of applications, including western blotting, immunohistochemistry, and flow cytometry. It has been validated for use in human, mouse, and rat samples, and exhibits minimal cross-reactivity with other related proteins. The antibody is provided as a liquid formulation in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative.

In summary, the ITGAX polyclonal antibody is a reliable and versatile tool for the detection and quantification of ITGAX protein expression in various biological samples. Its high specificity and sensitivity make it an ideal choice for researchers studying the role of ITGAX in immune function and disease.