SMAD6 Polyclonal Antibody

SMAD6 Polyclonal Antibody

The SMAD6 Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of SMAD6 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human SMAD6 protein. The resulting polyclonal antibody has been purified using protein A affinity chromatography and validated for its specificity and sensitivity in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The SMAD6 protein is a member of the SMAD family of proteins that play a crucial role in the TGF-β signaling pathway. SMAD6 acts as a negative regulator of TGF-β signaling by inhibiting the phosphorylation and activation of SMAD2 and SMAD3 proteins. Dysregulation of SMAD6 expression has been implicated in various diseases, including cancer, cardiovascular diseases, and osteoarthritis.

The SMAD6 Polyclonal Antibody is a valuable tool for researchers studying the TGF-β signaling pathway and its role in various physiological and pathological processes. Its high specificity and sensitivity make it an ideal choice for detecting SMAD6 protein expression in various biological samples. With its reliable performance and consistent results, this antibody is an essential reagent for any laboratory investigating the function of SMAD6 protein.