KRT2 Polyclonal Antibody

KRT2 Polyclonal Antibody

The KRT2 polyclonal antibody is a highly specific and sensitive tool for the detection and quantification of keratin 2 (KRT2) protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human KRT2 protein. The resulting polyclonal antibody is purified using protein A affinity chromatography and validated for its specificity and sensitivity using various techniques, including Western blotting, immunohistochemistry, and ELISA.

KRT2 is a member of the keratin family of intermediate filament proteins that are expressed in epithelial cells. It plays a crucial role in maintaining the structural integrity of the skin and hair. Abnormal expression or mutations in KRT2 have been associated with various skin disorders, including ichthyosis bullosa of Siemens and epidermolytic hyperkeratosis.

The KRT2 polyclonal antibody is a valuable tool for researchers studying the role of KRT2 in skin biology and pathology. It can be used to detect and quantify KRT2 protein expression in various tissues and cell types, including skin, hair, and nails. It can also be used to investigate the effects of KRT2 mutations on protein expression and function.

In summary, the KRT2 polyclonal antibody is a high-quality reagent that offers excellent specificity and sensitivity for the detection and quantification of KRT2 protein. It is an essential tool for researchers studying the role of KRT2 in skin biology and pathology.