JAM3 Polyclonal Antibody

JAM3 Polyclonal Antibody

The JAM3 polyclonal antibody is a highly specific and sensitive tool for the detection and quantification of Junctional Adhesion Molecule 3 (JAM3) in various biological samples. JAM3 is a transmembrane protein that plays a crucial role in the regulation of cell-cell adhesion and migration, as well as in the maintenance of endothelial barrier function. Dysregulation of JAM3 expression has been implicated in various pathological conditions, including inflammation, cancer, and cardiovascular diseases.

The JAM3 polyclonal antibody is produced by immunizing rabbits with a synthetic peptide corresponding to a specific region of the JAM3 protein. The resulting antibody is purified using a combination of protein A and protein G chromatography, ensuring high purity and specificity. The antibody has been extensively validated for use in various applications, including Western blotting, immunohistochemistry, and flow cytometry.

The JAM3 polyclonal antibody exhibits high sensitivity and specificity, with minimal cross-reactivity with other proteins. It has been shown to detect JAM3 in various cell types and tissues, including endothelial cells, leukocytes, and epithelial cells. The antibody is suitable for use in both research and diagnostic applications, and has been used in numerous studies investigating the role of JAM3 in various physiological and pathological processes.

In summary, the JAM3 polyclonal antibody is a reliable and versatile tool for the detection and quantification of JAM3 in various biological samples. Its high sensitivity and specificity make it an ideal choice for researchers and clinicians studying the role of JAM3 in health and disease.