KCNQ4 Polyclonal Antibody

KCNQ4 Polyclonal Antibody

The KCNQ4 Polyclonal Antibody is a highly specific and sensitive antibody that has been designed to detect and quantify the expression of KCNQ4 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human KCNQ4 protein. The resulting polyclonal antibody has been purified using a combination of protein A and protein G affinity chromatography to ensure high specificity and purity.

The KCNQ4 protein is a voltage-gated potassium channel that plays a critical role in regulating the excitability of various cells, including auditory hair cells, neurons, and cardiac myocytes. Mutations in the KCNQ4 gene have been associated with several inherited hearing disorders, including autosomal dominant nonsyndromic hearing loss and DFNA2. Therefore, the KCNQ4 Polyclonal Antibody is an essential tool for researchers studying the molecular mechanisms underlying these hearing disorders.

The KCNQ4 Polyclonal Antibody has been validated for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been shown to specifically recognize the KCNQ4 protein in human, mouse, and rat tissues. This antibody has also been tested in various cell lines, including HEK293, COS-7, and CHO cells, and has been shown to detect endogenous KCNQ4 protein expression.

In summary, the KCNQ4 Polyclonal Antibody is a highly specific and sensitive antibody that is essential for researchers studying the molecular mechanisms underlying inherited hearing disorders. Its high specificity and sensitivity make it an ideal tool for detecting and quantifying KCNQ4 protein expression in various biological samples.